Strategic Investment to Support Unshackled’s Growth

CVX Ventures is pleased to announce that two of our partners have made a strategic investment in Unshackled, a Netherlands-based med-tech startup developing heated wearable technology for individuals living with Raynaud’s syndrome.

This investment includes both capital and advisory support. The two partners bring valuable experience in areas such as supply chain operations, medical device compliance, and go-to-market strategy, and are now actively advising the Unshackled team as the company prepares for pilot testing and market entry.

A New Approach to Raynaud’s Treatment

Founded by Sebastian Nyrup and Piyush Gupta, Unshackled has created a smart, battery-powered glove designed to offer a non-invasive alternative to pharmaceutical treatment. The product delivers targeted warmth to improve comfort for Raynaud’s patients. The company has already secured a Proof of Principle grant from LIOF, as well as funding from the Dutch government to explore potential use cases in military settings. Unshackled also received the Maastricht Business Take Off Award and is preparing to generate its first commercial revenue this year.

How CVX Made the Connection

“Unshackled started with a clear mission to help people living with Raynaud’s. Early grants allowed us to prove the technology and gather feedback from users. But scaling a product like this and preparing for global compliance requires the right knowledge. That is why we pitched through CVX. Thanks to that process, we are now working with two experienced partners who are already making a difference,” said Sebastian Nyrup, CEO and Co-founder of Unshackled.

CVX Ventures connected Unshackled with the right expertise through our structured pitch and matching process. From pitch day to follow-up conversations and onboarding, our team worked closely with the founders to ensure a smooth and valuable outcome.

“CVX made every part of the journey clear and productive. From our first meeting to bringing our new advisors and investors on board, the support we received was hands-on and helpful,” Nyrup added.

Ready to Scale

With this new support, Unshackled is accelerating product development, securing intellectual property, and preparing for the regulatory steps required to bring their innovation to market. The company’s mission is to provide a simple and effective solution to a widespread condition and, in the process, help define a new category of wearable medical technology.

At CVX Ventures, we are proud to support this connection and continue to focus on enabling founders through access to capital and hands-on strategic talent from our partner network.

For more information, visit: https://www.linkedin.com/company/unshackled-bv/

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